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mouse TNFSF18 shRNA silencing AAV

Name 
AAV-m-TNFSF18-shRNA
Cat No 
shAAV-274731
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Tnfsf18.

shAAV-274731
AAV-m-TNFSF18-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tnfsf18 (tumor necrosis factor (ligand) superfamily, member 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Gitrl; Tnlg2a
Description (Vector)
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.
Gene ID
240873
Gene Name (Vector)
tumor necrosis factor (ligand) superfamily, member 18
Gene Symbol
Tnfsf18
ORF Size (aa)
522
ORF Size (bp)
522 bp
RefSeq ID
NM_183391
RefSeq Synonyms
NM_183391, BC137815, BC137814,
Species
mouse
UniGene ID
Mm.276823

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.