human TNFSF18 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TNFSF18.
shAAV-226109
AAV-h-TNFSF18-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TNFSF18 (tumor necrosis factor superfamily member 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
activation-inducible TNF-related ligand; AITR ligand; AITRL; GITR ligand; GITRL; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; hGITRL; TL6; TNLG2A; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand 2A; tumor necrosis factor ligand superfamily member 18; tumor necrosis factor superfamily member 18
Description (eCommerce)
GITR Ligand/TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for receptor TNFRSF18/AITR/GITR and has been shown to modulate T lymphocyte survival in peripheral tissues. GITR Ligand/TNFSF18 is also expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [taken from NCBI Entrez Gene (Gene ID: 8995)].
Description (Vector)
TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Gene ID
8995
Gene Name (eCommerce)
TNF superfamily member 18
Gene Name (Vector)
tumor necrosis factor superfamily member 18
Gene Symbol
TNFSF18
HGNC ID
HGNC:11932
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
534
Protein Name (eCommerce)
Tumor necrosis factor ligand superfamily member 18
RefSeq ID
NM_005092
RefSeq Synonyms
NM_005092, BC112032, BC093986, BC069319,
Research Areas
Apoptosis,Cancer,Immunology,Signal Transduction
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,immunology
Species
human
Target Sentence
GITR Ligand/TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for receptor TNFRSF18/AITR/GITR and has been shown to modulate T lymphocyte survival in peripheral tissues. GITR Ligand/TNFSF18 is also expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [taken from NCBI Entrez Gene (Gene ID: 8995)].
UniGene ID
Hs.248197
UniProt ID (eCommerce)
Q9UNG2
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.