mouse LDLR shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ldlr.
shADV-263355
Ad-m-LDLR-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ldlr (low density lipoprotein receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Hlb301
Description (Vector)
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
Gene ID
16835
Gene Name (Vector)
low density lipoprotein receptor
Gene Symbol
Ldlr
ORF Size (aa)
2589
ORF Size (bp)
2589 bp
RefSeq ID
NM_010700
RefSeq Synonyms
NM_010700, NM_001252659, NM_001252658, BC053041, BC019207,
Species
mouse
UniGene ID
Mm.3213
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.