human PMPCA Over-expression AAV

Name 
AAV-h-PMPCA
Cat No 
AAV-219276
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PMPCA.

AAV-219276
AAV-h-PMPCA

Ready-to-use AAV expressing Human PMPCA (peptidase, mitochondrial processing alpha subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Alpha-MPP; cerebellar ataxia 1 (autosomal recessive); Cerebellar ataxia-1; CLA1; CPD3; inositol polyphosphate-5-phosphatase, 72 kD; INPP5E; mitochondrial matrix processing protease, alpha subunit; mitochondrial-processing peptidase subunit alpha; P-55; SCAR2
Description (eCommerce)
PMPCA is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins [taken from NCBI Entrez Gene (Gene ID: 23203)].
Gene ID
23203
Gene Name (eCommerce)
peptidase, mitochondrial processing alpha subunit
Gene Name (Vector)
peptidase, mitochondrial processing alpha subunit
Gene Symbol
PMPCA
HGNC ID
HGNC:18667
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1578
ORF Size (bp)
1578 bp
Protein Name (eCommerce)
Mitochondrial-processing peptidase subunit alpha
RefSeq ID
NM_015160
RefSeq Synonyms
NM_015160, NM_001282946, NM_001282944, BC136599, BC132724, BC111399,
Research Areas
Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
PMPCA is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins [taken from NCBI Entrez Gene (Gene ID: 23203)].
UniGene ID
Hs.495471
UniProt ID (eCommerce)
Q10713

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.