human BIRC7 shRNA silencing Adenovirus

Name 
Ad-h-BIRC7-shRNA
Cat No 
shADV-202148
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human BIRC7.

shADV-202148
Ad-h-BIRC7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human BIRC7 (baculoviral IAP repeat containing 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
KIAP; LIVIN; ML-IAP; MLIAP; RNF50
Description (Vector)
BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.
Gene ID
79444
Gene Name (Vector)
baculoviral IAP repeat containing 7
Gene Symbol
BIRC7
HGNC ID
HGNC:13702
ORF Size (aa)
897
ORF Size (bp)
897 bp
RefSeq ID
NM_022161
RefSeq Synonyms
NM_139317, NM_022161, BC014475,
Species
human
UniGene ID
Hs.256126

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.