human NOX4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NOX4.
shADV-230059
Ad-h-NOX4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NOX4 (NADPH oxidase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
KOX; KOX-1; RENOX
Description (Vector)
NOX4 encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Gene ID
50507
Gene Name (Vector)
NADPH oxidase 4
Gene Symbol
NOX4
HGNC ID
HGNC:7891
ORF Size (aa)
1737
ORF Size (bp)
1737 bp
RefSeq ID
NM_016931
RefSeq Synonyms
NM_016931, NM_001300995, NM_001291929, NM_001291927, NM_001291926, NM_001143837, NM_001143836, BC040105,
Species
human
UniGene ID
Hs.371036
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.