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human DSCR4 Over-expression AAV

Name 
AAV-h-DSCR4
Cat No 
AAV-207342
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DSCR4.

AAV-207342
AAV-h-DSCR4

Ready-to-use AAV expressing Human DSCR4 (Down syndrome critical region 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DCRB; DSCRB
Description (Vector)
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. This gene is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta.
Gene ID
10281
Gene Name (Vector)
Down syndrome critical region 4
Gene Symbol
DSCR4
HGNC ID
HGNC:3045
ORF Size (aa)
357
RefSeq ID
NM_005867
RefSeq Synonyms
NM_005867, BC096164, BC096163, BC096162, BC069729,
Species
human
UniGene ID
Hs.23251

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.