human NOX4 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-230059
Availability:
6-8 weeks
Name:
AAV-h-NOX4-shRNA
This is an AAV expressing shRNA for silencing of Human NOX4.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- NOX4
- Gene Name
- NADPH oxidase 4
- Gene ID
- 50507
- Gene Synonyms
- KOX; KOX-1; RENOX
- ORF Size
- 1737 bp
- RefSeq#
- NM_016931
- Gene Description
- NOX4 encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
- UniGene ID
- Hs.371036
- HGNC ID
- HGNC:7891
Related Products
Product | Cat No. |
---|---|
AAV-h-NOX4 | AAV-230059 |
AAV-m-NOX4 | AAV-265956 |
Ad-h-NOX4 | ADV-230059 |
Ad-m-NOX4 | ADV-265956 |
AAV-m-NOX4-shRNA | shAAV-265956 |
Ad-h-NOX4-shRNA | shADV-230059 |
Ad-m-NOX4-shRNA | shADV-265956 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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