human TSEN2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TSEN2.
shAAV-226589
AAV-h-TSEN2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TSEN2 (tRNA splicing endonuclease subunit 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PCH2B; SEN2; SEN2L
Description (Vector)
TSEN2 encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
80746
Gene Name (Vector)
tRNA splicing endonuclease subunit 2
Gene Symbol
TSEN2
HGNC ID
HGNC:28422
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
RefSeq ID
NM_025265
RefSeq Synonyms
NM_025265, NM_001321279, NM_001321278, NM_001321277, NM_001145395, NM_001145394, NM_001145393, NM_001145392, BC019582, BC004211, BC004178,
Species
human
UniGene ID
Hs.335550
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.