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human TSEN2 shRNA silencing Adenovirus

Name 
Ad-h-TSEN2-shRNA
Cat No 
shADV-226589
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TSEN2.

shADV-226589
Ad-h-TSEN2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TSEN2 (tRNA splicing endonuclease subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PCH2B; SEN2; SEN2L
Description (Vector)
TSEN2 encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
80746
Gene Name (Vector)
tRNA splicing endonuclease subunit 2
Gene Symbol
TSEN2
HGNC ID
HGNC:28422
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
RefSeq ID
NM_025265
RefSeq Synonyms
NM_025265, NM_001321279, NM_001321278, NM_001321277, NM_001145395, NM_001145394, NM_001145393, NM_001145392, BC019582, BC004211, BC004178,
Species
human
UniGene ID
Hs.335550

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.