rat MASP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Masp1.
shADV-293768
Ad-r-MASP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Masp1 (mannan-binding lectin serine peptidase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Masp1/3; Masp3
Description (Vector)
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Gene ID
64023
Gene Name (Vector)
mannan-binding lectin serine peptidase 1
Gene Symbol
Masp1
ORF Size (aa)
1158
ORF Size (bp)
1158 bp
RefSeq ID
NM_022257
RefSeq Synonyms
NM_022257, BC085685,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.