rat SQSTM1 shRNA silencing Adenovirus

Name
Ad-r-SQSTM1-shRNA

Cat No
shADV-290128

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Sqstm1.

shADV-290128

Ad-r-SQSTM1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Sqstm1 (sequestosome 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Osi; ZIP; ZIP3

Description (Vector)

Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

Gene ID

113894

Gene Name (Vector)

sequestosome 1

Gene Symbol

Sqstm1

ORF Size (aa)

1320

ORF Size (bp)

1320 bp

RefSeq ID

NM_175843

RefSeq Synonyms

NM_181550, NM_175843, BC061575,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.