mouse SLC11A1 shRNA silencing Adenovirus

Name 
Ad-m-SLC11A1-shRNA
Cat No 
shADV-272062
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Slc11a1.

shADV-272062
Ad-m-SLC11A1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Bcg; ity; Ity; Ity1; Lsh; Nramp; Nramp1
Description (Vector)
Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.
Gene ID
18173
Gene Name (Vector)
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Gene Symbol
Slc11a1
ORF Size (aa)
1647
ORF Size (bp)
1647 bp
RefSeq ID
NM_013612
RefSeq Synonyms
NM_013612, BC109138, BC109137,
Species
mouse
UniGene ID
Mm.2913

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.