rat SLC11A1 shRNA silencing AAV

Name
AAV-r-SLC11A1-shRNA

Cat No
shAAV-294390

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Slc11a1.

shAAV-294390

AAV-r-SLC11A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Slc11a1 (solute carrier family 11 member 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Bcg; Itg; Lsh; Nramp1

Description (Vector)

Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

Gene ID

316519

Gene Name (Vector)

solute carrier family 11 member 1

Gene Symbol

Slc11a1

ORF Size (aa)

1524

ORF Size (bp)

1524 bp

RefSeq ID

NM_001031658

RefSeq Synonyms

NM_001031658, BC100653,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.