human SLC11A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SLC11A1.
shADV-223082
Ad-h-SLC11A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SLC11A1 (solute carrier family 11 member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LSH; NRAMP; NRAMP1
Description (Vector)
SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Gene ID
6556
Gene Name (Vector)
solute carrier family 11 member 1
Gene Symbol
SLC11A1
HGNC ID
HGNC:10907
ORF Size (aa)
1299
ORF Size (bp)
1299 bp
RefSeq ID
NM_000578
RefSeq Synonyms
NM_000578, BC071165,
Species
human
UniGene ID
Hs.591607
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.