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mouse SCYE1 shRNA silencing Adenovirus

Name 
Ad-m-SCYE1-shRNA
Cat No 
shADV-271484
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Aimp1.

shADV-271484
Ad-m-SCYE1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Aimp1 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
9830137A06Rik; AIMP1/p43; Emap2; EMAPII; p43; Scye1
Description (Vector)
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
Gene ID
13722
Gene Name (Vector)
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Gene Symbol
Aimp1
ORF Size (aa)
933
ORF Size (bp)
933 bp
RefSeq ID
NM_007926
RefSeq Synonyms
NM_007926, BC002054,
Species
mouse
UniGene ID
Mm.235137

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.