rat SCYE1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Aimp1.
shAAV-294107
AAV-r-SCYE1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Aimp1 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Emap2; Scye1
Description (Vector)
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
Gene ID
114632
Gene Name (Vector)
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Gene Symbol
Aimp1
ORF Size (aa)
948
ORF Size (bp)
948 bp
RefSeq ID
NM_053757
RefSeq Synonyms
NM_053757, BC098675,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.