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mouse MBTPS1 shRNA silencing Adenovirus

Name 
Ad-m-MBTPS1-shRNA
Cat No 
shADV-264339
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Mbtps1.

shADV-264339
Ad-m-MBTPS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mbtps1 (membrane-bound transcription factor peptidase, site 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
0610038M03Rik; AV003995; mKIAA0091; S1P; SKI-1; Ski1
Description (Vector)
Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu.
Gene ID
56453
Gene Name (Vector)
membrane-bound transcription factor peptidase, site 1
Gene Symbol
Mbtps1
ORF Size (aa)
3159
ORF Size (bp)
3159 bp
RefSeq ID
NM_019709
RefSeq Synonyms
NM_019709, NM_001167910, BC057198, BC054837,
Species
mouse
UniGene ID
Mm.206934

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.