mouse MBTPS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mbtps1.
shAAV-264339
AAV-m-MBTPS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mbtps1 (membrane-bound transcription factor peptidase, site 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0610038M03Rik; AV003995; mKIAA0091; S1P; SKI-1; Ski1
Description (Vector)
Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu.
Gene ID
56453
Gene Name (Vector)
membrane-bound transcription factor peptidase, site 1
Gene Symbol
Mbtps1
ORF Size (aa)
3159
ORF Size (bp)
3159 bp
RefSeq ID
NM_019709
RefSeq Synonyms
NM_019709, NM_001167910, BC057198, BC054837,
Species
mouse
UniGene ID
Mm.206934
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.