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human MBL2 shRNA silencing AAV

Name 
AAV-h-MBL2-shRNA
Cat No 
shAAV-215099
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MBL2.

shAAV-215099
AAV-h-MBL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MBL2 (mannose binding lectin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD
Description (Vector)
MBL2 encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Gene ID
4153
Gene Name (Vector)
mannose binding lectin 2
Gene Symbol
MBL2
HGNC ID
HGNC:6922
ORF Size (aa)
747
RefSeq ID
NM_000242
RefSeq Synonyms
NM_000242, BC096182, BC096181, BC096180, BC096179, BC069338,
Species
human
UniGene ID
Hs.499674

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.