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mouse MBL2 shRNA silencing AAV

Name 
AAV-m-MBL2-shRNA
Cat No 
shAAV-264321
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mbl2.

shAAV-264321
AAV-m-MBL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mbl2 (mannose-binding lectin (protein C) 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
L-MBP; MBL; MBL-C; MBP-C
Description (Vector)
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Gene ID
17195
Gene Name (Vector)
mannose-binding lectin (protein C) 2
Gene Symbol
Mbl2
ORF Size (aa)
735
ORF Size (bp)
735 bp
RefSeq ID
NM_010776
RefSeq Synonyms
NM_010776, BC010760,
Species
mouse
UniGene ID
Mm.30045

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.