mouse MAP3K8 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-264198
Availability:
5-8 weeks
Name:
Ad-m-MAP3K8-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Map3k8.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Map3k8
- Gene Name
- mitogen-activated protein kinase kinase kinase 8
- Gene ID
- 26410
- Gene Synonyms
- c-COT; Cot; Cot/Tpl2; Est; Estf; Tpl-2; Tpl2
- ORF Size
- 1404 bp
- RefSeq#
- NM_007746
- Gene Description
- Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle. The longer form has some transforming activity, although it is much weaker than the activated cot oncoprotein.
- UniGene ID
- Mm.3275
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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