mouse GRIA2 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-260750
Availability:
5-8 weeks
Name:
Ad-m-GRIA2-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Gria2.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Gria2
- Gene Name
- glutamate receptor, ionotropic, AMPA2 (alpha 2)
- Gene ID
- 14800
- Gene Synonyms
- GluA2; Glur-2; GluR-B; Glur2
- ORF Size
- 1485 bp
- RefSeq#
- NM_013540
- Gene Description
- Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate (By similarity).
- UniGene ID
- Mm.220224
Related Products
Product | Cat No. |
---|---|
AAV-h-GRIA2 | AAV-210506 |
AAV-m-GRIA2 | AAV-260750 |
Ad-h-GRIA2 | ADV-210506 |
Ad-m-GRIA2 | ADV-260750 |
AAV-h-GRIA2-shRNA | shAAV-210506 |
AAV-m-GRIA2-shRNA | shAAV-260750 |
Ad-h-GRIA2-shRNA | shADV-210506 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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