mouse FANCD2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Fancd2.
shADV-259148
Ad-m-FANCD2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fancd2 (Fanconi anemia, complementation group D2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2410150O07Rik; AU015151; BB137857; FA-D2; FA4; FACD; FAD; FANCD
Description (Vector)
Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Gene ID
211651
Gene Name (Vector)
Fanconi anemia, complementation group D2
Gene Symbol
Fancd2
ORF Size (aa)
4353
ORF Size (bp)
4353 bp
RefSeq ID
NM_001033244
RefSeq Synonyms
NM_001347350, NM_001033244, BC139004,
Species
mouse
UniGene ID
Mm.160061
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.