human DYNC1H1 shRNA silencing Adenovirus

Name 
Ad-h-DYNC1H1-shRNA
Cat No 
shADV-234074
Availability
5-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human DYNC1H1.

shADV-234074
Ad-h-DYNC1H1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DYNC1H1 (dynein cytoplasmic 1 heavy chain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CMT2O; cytoplasmic dynein 1 heavy chain 1; Cytoplasmic dynein heavy chain 1; DHC1; DHC1a; DNCH1; Dnchc1; DNCL; DNECL; DYHC; dynein heavy chain, cytosolic; dynein, cytoplasmic, heavy polypeptide 1; HL-3; p22; SMALED1
Description (eCommerce)
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains. DYNC1H1 is a member of the cytoplasmic dynein heavy chain family [taken from NCBI Entrez Gene (Gene ID: 1778)].
Description (Vector)
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family.
Gene ID
1778
Gene Name (eCommerce)
dynein cytoplasmic 1 heavy chain 1
Gene Name (Vector)
dynein cytoplasmic 1 heavy chain 1
Gene Symbol
DYNC1H1
HGNC ID
HGNC:2961
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
594
ORF Size (bp)
594 bp
Protein Name (eCommerce)
Cytoplasmic dynein 1 heavy chain 1
RefSeq ID
NM_001376
RefSeq Synonyms
NM_001376, BC064521,
Research Areas
Antigen Processing and Presentation,Apoptosis,Cell Cycle,Cytoskeleton,Golgi Apparatus,Immunology,Neurobiology,Neurodegeneration,Neurodevelopment,RNA Processing,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,immunology,neurobiology,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains. DYNC1H1 is a member of the cytoplasmic dynein heavy chain family [taken from NCBI Entrez Gene (Gene ID: 1778)].
UniProt ID (eCommerce)
Q14204

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.