human STIP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human STIP1.
shADV-224572
Ad-h-STIP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human STIP1 (stress induced phosphoprotein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HEL-S-94n; HOP; IEF-SSP-3521; P60; STI1; STI1L
Description (Vector)
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 (PubMed 16100115)).(supplied by OMIM, Jul 2009)
Gene ID
10963
Gene Name (Vector)
stress induced phosphoprotein 1
Gene Symbol
STIP1
HGNC ID
HGNC:11387
ORF Size (aa)
1773
ORF Size (bp)
1773 bp
RefSeq ID
NM_006819
RefSeq Synonyms
NM_006819, NM_001282653, NM_001282652, BC039299, BC002987,
Species
human
UniGene ID
Hs.337295
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.