human STIP1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-224572
Availability:
4-5 weeks
Name:
AAV-h-STIP1-shRNA
This is an AAV expressing shRNA for silencing of Human STIP1.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- STIP1
- Gene Name
- stress induced phosphoprotein 1
- Gene ID
- 10963
- Gene Synonyms
- HEL-S-94n; HOP; IEF-SSP-3521; P60; STI1; STI1L
- ORF Size
- 1773 bp
- RefSeq#
- NM_006819
- Gene Description
- STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 (PubMed 16100115)).(supplied by OMIM, Jul 2009)
- UniGene ID
- Hs.337295
- HGNC ID
- HGNC:11387
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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