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human SNX1 shRNA silencing Adenovirus

Name 
Ad-h-SNX1-shRNA
Cat No 
shADV-223911
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SNX1.

shADV-223911
Ad-h-SNX1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SNX1 (sorting nexin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HsT17379; sorting nexin 1A; sorting nexin-1; VPS5
Description (eCommerce)
Sorting nexin 1 (SNX1) is a component of the retromer complex that functions in endosome to trans-golgi network protein trafficking.
Description (Vector)
SNX1 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. SNX1 results in three transcript variants encoding distinct isoforms.
Gene ID
6642
Gene Name (eCommerce)
sorting nexin 1
Gene Name (Vector)
sorting nexin 1
Gene Symbol
SNX1
HGNC ID
HGNC:11172
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
Protein Name (eCommerce)
Sorting nexin-1
RefSeq ID
NM_003099
RefSeq Synonyms
NM_148955, NM_003099, NM_001242933, BC000357,
Research Areas
Golgi Apparatus,Signal Transduction,TGF-beta Signaling,Translational Control,Transport
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
Sorting nexin 1 (SNX1) is a component of the retromer complex that functions in endosome to trans-golgi network protein trafficking.
UniGene ID
Hs.188634
UniProt ID (eCommerce)
Q13596

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.