mouse SNX1 shRNA silencing AAV

Name
AAV-m-SNX1-shRNA

Cat No
shAAV-272787

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Snx1.

shAAV-272787

AAV-m-SNX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Snx1 (sorting nexin 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

SNX1 may be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).

Gene ID

56440

Gene Name (Vector)

sorting nexin 1

Gene Symbol

Snx1

ORF Size (aa)

1566

ORF Size (bp)

1566 bp

RefSeq ID

NM_019727

RefSeq Synonyms

NM_019727, BC066189, BC066044,

Species

mouse

UniGene ID

Mm.271891

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.