human N4BP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human N4BP1.
shADV-216262
Ad-h-N4BP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human N4BP1 (NEDD4 binding protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
N4BP1; NEDD4-binding protein 1
Description (eCommerce)
N4BP1 is an inhibitor of the E3 ubiquitin-protein ligase ITCH. N4BP1 ccts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity)Â [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75113].
Gene ID
9683
Gene Name (eCommerce)
NEDD4 binding protein 1
Gene Name (Vector)
NEDD4 binding protein 1
Gene Symbol
N4BP1
HGNC ID
HGNC:29850
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2691
ORF Size (bp)
2691 bp
Protein Name (eCommerce)
NEDD4-binding protein 1
RefSeq ID
NM_153029
RefSeq Synonyms
NM_153029, BC160019, BC152472,
Research Areas
Ubiquitination
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
N4BP1 is an inhibitor of the E3 ubiquitin-protein ligase ITCH. N4BP1 ccts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity)Â [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75113].
UniGene ID
Hs.511839
UniProt ID (eCommerce)
O75113
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.