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human N4BP1 Over-expression AAV

Name 
AAV-h-N4BP1
Cat No 
AAV-216262
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human N4BP1.

AAV-216262
AAV-h-N4BP1

Ready-to-use AAV expressing Human N4BP1 (NEDD4 binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
N4BP1; NEDD4-binding protein 1
Description (eCommerce)
N4BP1 is an inhibitor of the E3 ubiquitin-protein ligase ITCH. N4BP1 ccts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75113].
Gene ID
9683
Gene Name (eCommerce)
NEDD4 binding protein 1
Gene Name (Vector)
NEDD4 binding protein 1
Gene Symbol
N4BP1
HGNC ID
HGNC:29850
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2691
ORF Size (bp)
2691 bp
Protein Name (eCommerce)
NEDD4-binding protein 1
RefSeq ID
NM_153029
RefSeq Synonyms
NM_153029, BC160019, BC152472,
Research Areas
Ubiquitination
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
N4BP1 is an inhibitor of the E3 ubiquitin-protein ligase ITCH. N4BP1 ccts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75113].
UniGene ID
Hs.511839
UniProt ID (eCommerce)
O75113

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.