human HMGCS2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HMGCS2.
shADV-211285
Ad-h-HMGCS2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
3158
Gene Name (Vector)
3-hydroxy-3-methylglutaryl-CoA synthase 2
Gene Symbol
HMGCS2
HGNC ID
HGNC:5008
ORF Size (aa)
1527
ORF Size (bp)
1527 bp
RefSeq ID
NM_005518
RefSeq Synonyms
NM_005518, NM_001166107, BC044217,
Species
human
UniGene ID
Hs.59889
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.