human HMGCS2 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-211285
Availability:
6-8 weeks
Name:
AAV-h-HMGCS2-shRNA
This is an AAV expressing shRNA for silencing of Human HMGCS2.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HMGCS2
- Gene Name
- 3-hydroxy-3-methylglutaryl-CoA synthase 2
- Gene ID
- 3158
- ORF Size
- 1527 bp
- RefSeq#
- NM_005518
- Gene Description
- HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.59889
- HGNC ID
- HGNC:5008
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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