human ETFA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ETFA.
shADV-208133
Ad-h-ETFA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ETFA (electron transfer flavoprotein alpha subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EMA; GA2; MADD
Description (Vector)
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
2108
Gene Name (Vector)
electron transfer flavoprotein alpha subunit
Gene Symbol
ETFA
HGNC ID
HGNC:3481
ORF Size (aa)
1002
ORF Size (bp)
1002 bp
RefSeq ID
NM_000126
RefSeq Synonyms
NM_001127716, NM_000126, BC095457, BC015526,
Species
human
UniGene ID
Hs.39925
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.