rat HMGN1 shRNA silencing AAV

Name
AAV-r-HMGN1-shRNA

Cat No
shAAV-295184

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Hmgn1.

shAAV-295184

AAV-r-HMGN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Hmgn1 (high mobility group nucleosome binding domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).

Gene ID

360704

Gene Name (Vector)

high mobility group nucleosome binding domain 1

Gene Symbol

Hmgn1

ORF Size (aa)

291

ORF Size (bp)

291 bp

RefSeq ID

NM_001013184

RefSeq Synonyms

NM_001013184, BC086423,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.