rat CDKN1C shRNA silencing AAV

Name
AAV-r-CDKN1C-shRNA

Cat No
shAAV-294081

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Cdkn1c.

shAAV-294081

AAV-r-CDKN1C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Cdkn1c (cyclin-dependent kinase inhibitor 1C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Kip2; p57; p57KIP2

Description (Vector)

Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.

Gene ID

246060

Gene Name (Vector)

cyclin-dependent kinase inhibitor 1C

Gene Symbol

Cdkn1c

ORF Size (aa)

1032

ORF Size (bp)

1032 bp

RefSeq ID

NM_182735

RefSeq Synonyms

NM_182735, NM_001033758, NM_001033757, BC098646,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.