human CDKN1C shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-204879
Availability:
Immediate
Name:
Ad-h-CDKN1C-shRNA
This is an Adenovirus expressing shRNA for silencing of Human CDKN1C.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CDKN1C
- Gene Name
- cyclin dependent kinase inhibitor 1C
- Gene ID
- 1028
- Gene Synonyms
- BWCR; BWS; KIP2; p57; p57Kip2; WBS
- ORF Size
- 951 bp
- RefSeq#
- NM_000076
- Gene Description
- CDKN1C is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
- UniGene ID
- Hs.106070
- HGNC ID
- HGNC:1786
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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