mouse PPARGC1A shRNA silencing AAV

Name 
AAV-m-PPARGC1A-shRNA
Cat No 
shAAV-280991
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ppargc1a.

shAAV-280991
AAV-m-PPARGC1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ppargc1a (peroxisome proliferative activated receptor, gamma, coactivator 1 alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A830037N07Rik; ENSMUSG00000079510; Gm11133; PGC-1; Pgc-1alpha; Pgc1; Pgco1; PPARGC-1-alpha; Ppargc1
Description (Vector)
Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis.
Gene ID
19017
Gene Name (Vector)
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Gene Symbol
Ppargc1a
ORF Size (aa)
2394
ORF Size (bp)
2394 bp
RefSeq ID
NM_008904
RefSeq Synonyms
NM_008904, BC066868,
Species
mouse
UniGene ID
Mm.441196

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.