mouse PPARGC1A Adenovirus
This is an Adenovirus expressing Mouse Ppargc1a.
ADV-280991
Ad-m-PPARGC1A
Ready-to-use Adenovirus expressing Mouse Ppargc1a (peroxisome proliferative activated receptor, gamma, coactivator 1 alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A830037N07Rik; ENSMUSG00000079510; Gm11133; PGC-1; Pgc-1alpha; Pgc1; Pgco1; PPARGC-1-alpha; Ppargc1
Description (Vector)
Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis.
Gene ID
19017
Gene Name (Vector)
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Gene Symbol
Ppargc1a
ORF Size (aa)
2394
ORF Size (bp)
2394 bp
RefSeq ID
NM_008904
RefSeq Synonyms
NM_008904, BC066868,
Species
mouse
UniGene ID
Mm.441196
Related Citations
- Essential role of PGC-1a/PPARß axis in Ucp3 gene induction. TI Lima, etc, (2019), The Journal of Physiology
- Opposing action of NCoR1 and PGC-1a in mitochondrial redox homeostasis. TI Lima, etc, (2019), Free Radical Biology and Medicine
- A Novel Mitophagy Assay for Skeletal Myotubes. M Webb, etc, (2018), J Neurol Neurosurg
- The transcriptional coactivator PGC1a protects against hyperthermic stress via cooperation with the heat shock factor HSF. L Xu, X Ma, A Bagattin, E Muelle, (2016), Cell Death & Disease
- PGC-1a Induces Human RPE Oxidative Metabolism and Antioxidant CapacityPGC-1a Controls RPE Metabolism. Jared Iacovelli, etc, (2016), Investigative Ophthalmology & Visual Science
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.