mouse TFAM shRNA silencing AAV

Name 
AAV-m-TFAM-shRNA
Cat No 
shAAV-274078
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Tfam.

shAAV-274078
AAV-m-TFAM-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tfam (transcription factor A, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI661103; Hmgts; mtTFA; tsHMG
Description (Vector)
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M. Associates with mitochondrial DNA.
Gene ID
21780
Gene Name (Vector)
transcription factor A, mitochondrial
Gene Symbol
Tfam
ORF Size (aa)
732
ORF Size (bp)
732 bp
RefSeq ID
NM_009360
RefSeq Synonyms
NM_009360, BC083084, BC001987,
Species
mouse
UniGene ID
Mm.229292

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.