mouse NOC2L shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Noc2l.
shAAV-265904
AAV-m-NOC2L-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Noc2l (nucleolar complex associated 2 homolog (S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA410003; AF155546; NIR
Description (Vector)
Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.
Gene ID
57741
Gene Name (Vector)
nucleolar complex associated 2 homolog (S. cerevisiae)
Gene Symbol
Noc2l
ORF Size (aa)
2244
ORF Size (bp)
2244 bp
RefSeq ID
NM_021303
RefSeq Synonyms
NM_021303, BC020013,
Species
mouse
UniGene ID
Mm.423051
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.