mouse CMKLR1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cmklr1.
shAAV-255718
AAV-m-CMKLR1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cmklr1 (chemokine-like receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ChemR23; DEZ; Gpcr27; mcmklr1
Description (Vector)
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
Gene ID
14747
Gene Name (Vector)
chemokine-like receptor 1
Gene Symbol
Cmklr1
ORF Size (aa)
1116
ORF Size (bp)
1116 bp
RefSeq ID
NM_008153
RefSeq Synonyms
NM_008153, BC100612,
Species
mouse
UniGene ID
Mm.5196
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.