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mouse CMKLR1 Over-expression AAV

Name 
AAV-m-CMKLR1
Cat No 
AAV-255718
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cmklr1.

AAV-255718
AAV-m-CMKLR1

Ready-to-use AAV expressing Mouse Cmklr1 (chemokine-like receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ChemR23; DEZ; Gpcr27; mcmklr1
Description (Vector)
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
Gene ID
14747
Gene Name (Vector)
chemokine-like receptor 1
Gene Symbol
Cmklr1
ORF Size (aa)
1116
ORF Size (bp)
1116 bp
RefSeq ID
NM_008153
RefSeq Synonyms
NM_008153, BC100612,
Species
mouse
UniGene ID
Mm.5196

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.