mouse 2610109H07RIK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Draxin.
shAAV-250804
AAV-m-2610109H07RIK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Draxin (dorsal inhibitory axon guidance protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610109H07Rik; neucrin
Description (Vector)
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway (By similarity).
Gene ID
70433
Gene Name (Vector)
dorsal inhibitory axon guidance protein
Gene Symbol
Draxin
ORF Size (aa)
1032
ORF Size (bp)
1032 bp
RefSeq ID
NM_027426
RefSeq Synonyms
NM_027426, BC060239,
Species
mouse
UniGene ID
Mm.275288
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.