human TTL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TTL.
shAAV-226738
AAV-h-TTL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TTL (tubulin tyrosine ligase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 (PubMed 14571137)).(supplied by OMIM, Mar 2008)
Gene ID
150465
Gene Name (Vector)
tubulin tyrosine ligase
Gene Symbol
TTL
HGNC ID
HGNC:21586
ORF Size (aa)
1134
RefSeq ID
NM_153712
RefSeq Synonyms
NM_153712, BC036819,
Species
human
UniGene ID
Hs.358997
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.