human NMNAT3 shRNA silencing AAV

Name 
AAV-h-NMNAT3-shRNA
Cat No 
shAAV-216831
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NMNAT3.

shAAV-216831
AAV-h-NMNAT3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NMNAT3 (nicotinamide nucleotide adenylyltransferase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FKSG76; PNAT-3; PNAT3
Description (Vector)
NMNAT3 encodes a member of the nicotinamide/nicotinic acid mononucleotide adenylyltransferase family. These enzymes use ATP to catalyze the synthesis of nicotinamide adenine dinucleotide or nicotinic acid adenine dinucleotide from nicotinamide mononucleotide or nicotinic acid mononucleotide, respectively. The encoded protein is localized to mitochondria and may also play a neuroprotective role as a molecular chaperone. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
349565
Gene Name (Vector)
nicotinamide nucleotide adenylyltransferase 3
Gene Symbol
NMNAT3
HGNC ID
HGNC:20989
ORF Size (aa)
648
RefSeq ID
NM_178177
RefSeq Synonyms
NM_178177, NM_001320513, NM_001320512, NM_001320511, NM_001320510, NM_001200047, BC036218, BC034374,
Species
human
UniGene ID
Hs.208673

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.