human HDAC9 shRNA silencing AAV

Name
AAV-h-HDAC9-shRNA

Cat No
shAAV-210895

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human HDAC9.

shAAV-210895

AAV-h-HDAC9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HDAC9 (histone deacetylase 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; MITR

Description (Vector)

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

Gene ID

9734

Gene Name (Vector)

histone deacetylase 9

Gene Symbol

HDAC9

HGNC ID

HGNC:14065

ORF Size (aa)

1773

ORF Size (bp)

1773 bp

RefSeq ID

NM_014707

RefSeq Synonyms

NM_178425, NM_178423, NM_058176, NM_014707, NM_001321902, NM_001321901, NM_001321900, NM_001321899, NM_001321898, NM_001321897, NM_001321896, NM_001321895, NM_001321894, NM_001321893, NM_001321891, NM_001321890, NM_001321889, NM_001321888, NM_001321887, NM_001321886, NM_001321885, NM_001321884, NM_001321879, NM_001321878, NM_001321877, NM_001321876, NM_001321875, NM_001321874, NM_001321873, NM_001321872, NM_001321871, NM_001321870, NM_001321869, NM_001321868, NM_001204148, NM_001204147, NM_001204146, NM_001204145, NM_001204144, BC152405, BC150328,

Species

human

UniGene ID

Hs.196054

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.