mouse HDAC9 shRNA silencing Adenovirus

Name 
Ad-m-HDAC9-shRNA
Cat No 
shADV-261182
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Hdac9.

shADV-261182
Ad-m-HDAC9-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hdac9 (histone deacetylase 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
73
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AV022454; D030072B18Rik; HD7B; HD9; Hdac7b; HDRP; Mitr; mKIAA0744
Description (Vector)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription|Function: Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.
Gene ID
79221
Gene Name (Vector)
histone deacetylase 9
Gene Symbol
Hdac9
ORF Size (aa)
1767
ORF Size (bp)
1767 bp
RefSeq ID
NM_024124
RefSeq Synonyms
NM_024124, NM_001271386, BC098187,
Species
mouse
UniGene ID
Mm.310551

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.