human GYPA shRNA silencing AAV

Name
AAV-h-GYPA-shRNA

Cat No
shAAV-210703

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GYPA.

shAAV-210703

AAV-h-GYPA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GYPA (glycophorin A (MNS blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD235a; GPA; GPErik; GPSAT; HGpMiV; HGpMiXI; HGpSta(C); MN; MNS; PAS-2

Description (Vector)

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.

Gene ID

2993

Gene Name (Vector)

glycophorin A (MNS blood group)

Gene Symbol

GYPA

HGNC ID

HGNC:4702

ORF Size (aa)

453

RefSeq ID

NM_002099

RefSeq Synonyms

NM_002099, NM_001308190, NM_001308187, BC013328, BC005319,

Species

human

UniGene ID

Hs.434973

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.