human PSRC1 Adenovirus

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PSRC1

Gene Name

proline and serine rich coiled-coil 1

Gene ID

84722

Gene Synonyms

DDA3; FP3214

ORF Size

1092 bp

RefSeq#

BC056909

Gene Description

PSRC1 encodes a proline-rich protein. Studies of this gene and the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. The encoded protein may function as a microtubule destabilizing protein that controls spindle dynamics and mitotic progression by recruiting and regulating microtubule depolymerases. At least one genetic variation in this gene has been associated with decreased serum levels of low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding different isoforms have been described.

UniGene ID

Hs.405925

HGNC ID

HGNC:24472